The Bruce Highway has been closed in both directions at Bororen, south of Gladstone, following a two-vehicle crash involving a truck carrying hazardous materials.
The incident occurred at the intersection of the Bruce Highway and Daisy Dell Road at about 5.15am.
According to reports, a B-double tanker carrying ammonium nitrate and a ute were involved in a head-on collision, causing the tanker to burst into flames.
The Queensland Ambulance Service reports that one patient is being assessed for life-threatening injuries, and the other is in a serious but stable condition.
Emergency services remain on the scene, with a helicopter also deployed.
Nearby homes have been evacuated, with a 2.5km exclusion zone in place. The Queensland Fire Department has issued an alert saying that anyone who is in the area should leave immediately.
If you cannot leave, shelter indoors, and close your windows and doors, and turn off your air conditioning.
The road is currently closed in both directions, with motorists asked to avoid the area and seek alternative travel routes.
Long delays are expected. For up to date travel information, visit QLD Traffic.
The incident is the latest in a tragic series of Bruce Highway accidents involving truckies this week, one of which resulted in the loss of a 29-year-old who died in Gladstone Hospital on Wednesday night.
More to come.
Apparently trailer has exploded